Deoxy-thalidomide-OMe

• Description :

  Deoxy-thalidomide-OMe is an E3 ligase ligand. Deoxy-thalidomide-OMe can be used for synthesis of PROTAC LRRK2 Degrader-4 (HY-178796) [1].

• UNSPSC :

  12352005

• Target :

  Ligands for E3 Ligase

• Related Pathways :

  PROTAC

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Smiles :

  COC1=CC=CC2=C1CN(C2=O)C3CCC(NC3=O)=O

• Molecular Formula :

  C14H14N2O4

• Molecular Weight :

  274.27

• References & Citations :

  [1]Renner A C, et al. LRRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration[J]. ACS Medicinal Chemistry Letters, 2025.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1061605-49-9]