Deoxy-thalidomide-OMe

• Description:

  Deoxy-thalidomide-OMe is an E3 ligase ligand. Deoxy-thalidomide-OMe can be used for synthesis of PROTAC LRRK2 Degrader-4 (HY-178796) [1].

• UNSPSC:

  12352005

• Target:

  Ligands for E3 Ligase

• Related Pathways:

  PROTAC

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  COC1=CC=CC2=C1CN(C2=O)C3CCC(NC3=O)=O

• Molecular Formula:

  C14H14N2O4

• Molecular Weight:

  274.27

• References & Citations:

  [1]Renner A C, et al. LRRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration[J]. ACS Medicinal Chemistry Letters, 2025.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1061605-49-9]