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OV329 (hydrochloride)

CAT: 0804-HY-179215-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-179215-01Size:5 mg
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Description
OV329 hydrochloride is a potent GABA aminotransferase inactivator. OV329 hydrochloride is a Vigabatrin analogue. OV329 hydrochloride can increase brain GABA levels and block abnormal intracerebral hyperexcitability. OV329 hydrochloride exhibits anticonvulsant and antiepileptic activities. OV329 hydrochloride can be used for the research of neurological disease, such as seizure[1].
CAS Number
2093928-29-9
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.83
Smiles
N[C@H]1C=C(C/C1=C(F)\F)C(O)=O.Cl
Molecular Formula
C7H8ClF2NO2
Molecular Weight
211.59
References & Citations
[1]Feja M, et al. OV329, a novel highly potent γ-aminobutyric acid aminotransferase inactivator, induces pronounced anticonvulsant effects in the pentylenetetrazole seizure threshold test and in amygdala-kindled rats. Epilepsia. 2021 Dec;62 (12) :3091-3104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Kt-II-115 hydrochloride
CAS Number2093928-29-9
PubChem CID141518249
IUPAC Name(3S)-3-amino-4-(difluoromethylidene)cyclopentene-1-carboxylic acid;hydrochloride
Molecular FormulaC7H8ClF2NO2
Molecular Weight211.59
Topological Polar Surface Area63.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Heavy Atom Count13
Formal Charge0
Complexity279
SMILES
C1C(=C[C@@H](C1=C(F)F)N)C(=O)O.Cl
InChI
InChI=1S/C7H7F2NO2.ClH/c8-6(9)4-1-3(7(11)12)2-5(4)10;/h2,5H,1,10H2,(H,11,12);1H/t5-;/m0./s1
InChIKey
PGDQYCPAAUSFPP-JEDNCBNOSA-N
Chemical Structure
2D Structure
2D structure of Kt-II-115 hydrochloride
CAS: 2093928-29-9
CID: 141518249
Formula: C7H8ClF2NO2
MW: 211.59
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight211.59
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass211.0211625
Monoisotopic Mass211.0211625
Topological Polar Surface Area63.3 Ų
Heavy Atom Count13
Formal Charge0
Complexity279
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes