Thalidomide-C4-N2-C2-N3

CAT: 0804-HY-179168Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179168Size:1 Each
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Description
Thalidomide-C4-N2-C2-N3 is an E3 ligase ligand. Thalidomide-C4-N2-C2-N3 can bind to a target protein ligand with a linker to form a PROTAC molecule, PROTAC sEH-degrader-4 (HY-179166) [1].
CAS Number
[2825005-43-2]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=C2C=CC(N3CCN(CCN=[N+]=[N-])CC3)=C1)N(C(CC4)C(NC4=O)=O)C2=O
Molecular Formula
C19H21N7O4
Molecular Weight
411.41
References & Citations
[1]Schönfeld J, et al. Click chemistry enables rapid development of potent sEH PROTACs using a direct-to-biology approach. Chem Commun (Camb) . 2025 Nov 13;61 (92) :18108-18111.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

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