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P2Y12/PDE5-IN-1

CAT: 0804-HY-179053Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179053Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P2Y12/PDE5-IN-1 (Compound 10) is a dual-target inhibitor of P2Y12 (IC50 = 0.271 μg/mL) and PDE5 (IC50 = 0.154 μg/mL) . P2Y12/PDE5-IN-1 can be used for research on anti-thrombosis and vasodilation[1].
UNSPSC
12352005
Target
P2Y Receptor; Phosphodiesterase (PDE)
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C1N(C2CCCCC2)C(C=C(/N=C\C3=CC=C(Cl)C=C3Cl)N1C4CCCCC4)=O
Molecular Formula
C23H27Cl2N3O2
Molecular Weight
448.39
References & Citations
[1]Elsayed DA, et al. Antiplatelet therapy through inhibition of P2Y12 and phosphodiesterase receptors by novel synthesis 1,3-dicyclohexylpyrimidine-2,4 (1H,3H) -dione derivatives with computational evaluation. Bioorg Chem. 2025 Oct;165:109009.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y12 Receptor; PDE5

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