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CYP3A4-IN-6

CAT: 0804-HY-179011Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179011Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYP3A4-IN-6 (Compound 8a) is a CYP3A4 inhibitor with tissue-selective metabolism. CYP3A4-IN-6 remains stable in the intestinal S9 component but is rapidly metabolized in the liver S9 component, forming a less active metabolite. CYP3A4-IN-6 can be used for intestinal selectivity studies[1].
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(C1=CC=C(C=C1)COCC2=CC=C(C=C2)N3C=CN=C3)OC
Molecular Formula
C19H18N2O3
Molecular Weight
322.36
References & Citations
[1]Elsayed DA, et al. Antiplatelet therapy through inhibition of P2Y12 and phosphodiesterase receptors by novel synthesis 1,3-dicyclohexylpyrimidine-2,4 (1H,3H) -dione derivatives with computational evaluation. Bioorg Chem. 2025 Oct;165:109009.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP3

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