NOD2 agonist 4

• Description :

  NOD2 agonist 4 (Compound 12b) is a potent NOD2 agonist with an EC50 of 44.1 nM. NOD2 agonist 4 induces cytokine production (MCP-1, IL-6 and IL-8) in peripheral blood mononuclear cells (PBMCs), both alone and in combination with Lipopolysaccharide (LPS) (HY-D1056) . NOD2 agonist 4 can be used for the studies of NOD2-targeted immunomodulator or vaccine adjuvant[1].

• UNSPSC :

  12352211

• Target :

  Interleukin Related; NOD-like Receptor (NLR)

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  [][Fe][].O=C(Cc1cccc1)NCC(N[C@@H](C(C)C)C(N[C@H](CCC(OCC)=O)C(OCC)=O)=O)=O.c2cccc2

• Molecular Formula :

  C28H39FeN3O7

• Molecular Weight :

  585.47

• References & Citations :

  [1]Car Z, et al. Ferrocene-Containing Desmuramylpeptides Adopt A Flexible Conformation and Exhibit NOD2 Agonistic Activity. Organometallics. 2025 Oct 22.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  IL-6; IL-8; NOD2