Antibacterial agent 299

• Description :

  Antibacterial agent 299 (Compound P5) is a highly effective antibacterial agent against Xanthomonas oryzae pv. oryzae (Xoo), with an EC₅₀ value of 6.9 μg/mL. Antibacterial agent 299 integrates into bacterial membranes, disrupts membrane structure, inhibits biofilm formation, and thus exerts antibacterial effects. Antibacterial agent 299 also shows inhibitory activity against Xanthomonas oryzae pv. oryzicola (Xoc) (EC₅₀ = 32.5 ± 3.0 μg/mL), but its activity against Xanthomonas axonopodis pv. citri (Xac) is weaker. Antibacterial agent 299 demonstrated excellent control efficacy in a rice bacterial blight (BLB) model. Antibacterial agent 299 can be used for BLB research[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  FC(F)(C1=CC(C(N2CCN(CCOC3=CC(OC)=CC(C(C)=O)=C3)CC2)=O)=CC=C1)F

• Molecular Formula :

  C23H25F3N2O4

• Molecular Weight :

  450.45

• References & Citations :

  [1]Zheng Y, et al. Design, Synthesis, and Antibacterial Activity of Novel Paeonol Derivatives Containing Piperazine Moiety. J Agric Food Chem. 2025 Oct 29;73 (43) :27318-27327.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported