L-Valine-d7

• Description:

  L-Valine-d7 is the deuterium labeled L-Valine (HY-N0717) . L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

• UNSPSC:

  12352100

• Target:

  Akt; Arginase; Bacterial; Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

• Field of Research:

  Infection

• Smiles:

  [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])[C@H](N)C(O)=O

• Molecular Formula:

  C5H4D7NO2

• Molecular Weight:

  124.19

• References & Citations:

  [1]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6. |[2]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36. |[3]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1021439-16-6