L-Valine

• Description :

  L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

• Product Name Alternative :

  (S) -Valine

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Akt; Arginase; Bacterial

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; PI3K/Akt/mTOR

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/L-Valine.html

• Purity :

  99.89

• Solubility :

  H2O : 20 mg/mL (ultrasonic)

• Smiles :

  N[C@@H](C(C)C)C(O)=O

• Molecular Formula :

  C5H11NO2

• Molecular Weight :

  117.15

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6. |[2]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36.|[3]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number :

  [72-18-4]