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L-Valine-d

CAT: 0804-HY-178305SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178305SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Valine-d is the deuterium labeled L-Valine. L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].
CAS Number
79168-22-2
UNSPSC
12352100
Target
Akt; Arginase; Bacterial; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
CC(C)([2H])[C@H](N)C(O)=O
Molecular Formula
C5H10DNO2
Molecular Weight
118.15
References & Citations
[1]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6. |[2]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36. |[3]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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RPMI-2653-01RPMI 1640 with D-valine instead of L-valine
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EMEM-0607-01Eagle’s MEM with D-valine instead of L-valine
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DMHF-1883-01DMEM/F-12 with D-valine instead of L-valine
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