L-Phenylalanine-d

CAT: 0804-HY-178251SSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-178251SSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
L-Phenylalanine-d is the deuterium labeled L-Phenylalanine (HY-N0215) . L-Phenylalanine ((S) -2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca2+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
CAS Number
[55836-70-9]
UNSPSC
12352005
Target
Calcium Channel; Endogenous Metabolite; iGluR; Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Cancer; Metabolic Disease
Smiles
OC([C@](N)([2H])CC1=CC=CC=C1)=O
Molecular Formula
C9H10DNO2
Molecular Weight
166.20
References & Citations
[1]Glushakov AV, et al. Long-term changes in glutamatergic synaptic transmission in phenylketonuria. Brain. 2005 Feb;128 (Pt 2) :300-7. |[2]Glushakov AV, et al. L-phenylalanine selectively depresses currents at glutamatergic excitatory synapses. J Neurosci Res. 2003 Apr 1;72 (1) :116-24. |[3]Glushakov AV, et al. Specific inhibition of N-methyl-D-aspartate receptor function in rat hippocampal neurons by L-phenylalanine at concentrations observed during phenylketonuria. Mol Psychiatry. 2002;7 (4) :359-67.|[4]Mortell KH, et al. Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16 (5) :1138-41.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W152405-01D-Alanyl-L-phenylalanine
HY-N0215-01L-Phenylalanine
HY-Y0079-01D-Phenylalanine
HY-107378-01L-Valyl-L-phenylalanine
HY-23093-01L-Aspartyl-L-phenylalanine
HY-N0215R-01L-Phenylalanine (Standard)
HY-N0215S1-01L-Phenylalanine-d8
HY-118391-01Benzoyl-L-phenylalanine
HY-N0215S-01L-Phenylalanine-d7
HY-N0215S5-01L-Phenylalanine-15N

Alternative Products

CatalogName
OR1041540-01D-Alanyl-L-phenylalanine
B1077-804-Benzoyl-D, L-phenylalanine, Hydrochloride (D, L-BPA)
MBS6083521-014-Benzoyl-D,L-phenylalanine, Hydrochloride (D,L-BPA)
sc-5034084-Benzoyl-D, L-phenylalanine Hydrochloride
ST1469-50gL-Phenylalanine
11557-32L- (-) -Phenylalanine

Popular Products