L-Aspartyl-L-phenylalanine

• UNSPSC Description:

  L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM[1].

• Target Antigen:

  Angiotensin-converting Enzyme (ACE); Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-aspartyl-l-phenylalanine.html

• Purity:

  98.0

• Solubility:

  DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  OC(C[C@H](N)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)=O

• Molecular Weight:

  280.28

• References & Citations:

  [1]Grobelny D, et, al. A metabolite of aspartame inhibits angiotensin converting enzyme. Biochem Biophys Res Commun. 1985 Apr 30;128(2):960-4.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  13433-09-5