DTA-64 (sodium)

• Description :

  DTA-64 sodium is a aptamer targeted DEK. It significantly reduces joint inflammation in zymosan-induced arthritis mouse model and greatly impairs the ability of neutrophils to form neutrophil extracellular traps (NETs) . DEK is a secreted protein abundant

• UNSPSC :

  12352208

• Target :

  Others

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  [DTA-64(sodium)]

• References & Citations :

  [1]Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM. DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. Nat Commun. 2017 Feb 6;8:14252.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported