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KAT6-IN-4

CAT: 0804-HY-177445Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177445Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KAT6-IN-4 (Compound Example 2) is a selective lysine acetyltransferase 6 (KAT6) inhibitor. KAT6-IN-4 suppresses transcription of oncogenes like ERα. KAT6-IN-4 demonstrates potent antitumor efficacy in ER+/HER2- breast cancer xenografts. KAT6-IN-4 is promising for research of KAT6-driven malignancies (e.g., breast cancer, NSCLC) [1].
CAS Number
2901797-38-2
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Histone Acetyltransferase
Related Pathways
Epigenetics; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=S(NC1=NOC2=CC(CN3N=CC=C3)=C4C(OCCC4)=C21)(C5=C(OC)C=CC=C5OC)=O
Molecular Formula
C22H22N4O6S
Molecular Weight
470.50
References & Citations
[1]Zhang XM, et al. Sulfonamide derivative, preparation method therefor and medical use thereof. WO2023016484A1. 2023-02-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα

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