KAT6A/KAT7-IN-2

• Description:

  KAT6A/KAT7-IN-2 (Example 177) is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-2 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-2 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-2 also inhibits tumor cell proliferation, with an IC50 of ≤ 100 nM for CAMA-1. KAT6A/KAT7-IN-2 can be used in the study of cancer[1].

• UNSPSC:

  12352005

• Target:

  Histone Acetyltransferase

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(NC)C1=CC(OC)=C(S(=O)(NC2=NOC3=C2CC4(C5=C3C=C(N6CCC6)C=C5)CC4)=O)C(OC)=C1

• Molecular Formula:

  C26H28N4O6S

• Molecular Weight:

  524.59

• References & Citations:

  [1]Brian Thomas Jones, et al. Chemical compounds and uses thereof. WO2025136811A1. 2025-06-26.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3092066-69-5]