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KAT6A/KAT7-IN-1

CAT: 0804-HY-177043Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177043Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KAT6A/KAT7-IN-1 (Example 113) is a KAT6A and KAT7 inhibitor. The IC50 of KAT6A/KAT7-IN-1 for KAT6A is > 1 nM but ≤ 10 nM, while the IC50 for KAT7 is ≤ 1 nM. KAT6A/KAT7-IN-1 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-1 also inhibits tumor cell proliferation, with an IC50 of > 2 μM but ≤ 5 μM for CAMA-1. KAT6A/KAT7-IN-1 can be used in the study of cancer[1].
UNSPSC
12352005
Target
Histone Acetyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=S(C1=C(OC)C=CC=C1OC)(NC2=NOC3=C2CC4(C5=C3C=C(N6C(CCC6)=O)C=C5)CC4)=O
Molecular Formula
C25H25N3O6S
Molecular Weight
495.55
References & Citations
[1]Brian Thomas Jones, et al. Chemical compounds and uses thereof. WO2025136811A1. 2025-06-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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