Products for Research Use Only
RegisterLogin

E3 ligase Ligand 76

CAT: 0804-HY-176917Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-176917Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
E3 ligase Ligand 76 is a E3 ligase ligand that can be used in the recruitment of VHL protein. E3 ligase Ligand 76 can be connected to the KRAS ligand by a linker to synthesis of PROTAC KRAS (on) degrader ACBI-4 (HY-176792).
UNSPSC
12352211
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@H]1CN[C@@H](C1)C(NCC2=CC=C3C(N(C)N=C3)=C2)=O.Cl
Molecular Formula
C14H19ClN4O2
Molecular Weight
310.78
References & Citations
[1]Vetma V, et al. Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-Loaded KRAS (On) Alleles. J Am Chem Soc. 2025 Oct 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)

Related Products

CatalogName
HY-168865E3 ligase Ligand 53
HY-W890189E3 ligase Ligand 54
HY-W245311-01E3 ligase Ligand 51
HY-W382038-01E3 ligase Ligand 32
HY-W1003189E3 ligase Ligand 42
HY-170986E3 ligase Ligand 57
HY-170861E3 ligase Ligand 58
HY-170449E3 ligase Ligand 48
HY-170371E3 ligase Ligand 47
HY-161639E3 ligase Ligand 26

Alternative Products

CatalogName
YSB56068-01E3 Ligase ligand 10
RPD48943-01E3 Ligase ligand 14
AZB38333E3 Ligase ligand 8
T207614-01E3 ligase Ligand 66
T207279-01E3 ligase Ligand 64
T206200-01E3 ligase Ligand 59
T205399-01E3 ligase Ligand 56
T204160-01E3 ligase Ligand 48
T201674-01E3 ligase Ligand 42
T201474-01E3 ligase Ligand 40

Popular Products