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KIT-13

CAT: 0804-HY-176266Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176266Size:1 Each
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Description
KIT-13 is an orally active plasmalogen derivative to inhibit neuroinflammation and mitochondrial DNA leakage associated with Mecp2 deficiency. KIT-13 significantly reduce neurological symptoms and improves the life span of the Rett Syndrome (RTT) model mice. KIT-13 can be used for the study of RTT and other neuroinflammation-related diseases[1].
UNSPSC
12352211
Target
Mitochondrial Metabolism
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](CO[P@]([O-])(OCC[NH3+])=O)COCCCCCCCCCCCCCCCCCC)=O
Molecular Formula
C43H80NO7P
Molecular Weight
754.07
References & Citations
[1]Akane Matsuda, et al. Novel plasmalogen derivative KIT-13 restores neurological function in a mouse model of Rett syndrome by reducing neuroinflammation and restoring mitochondrial function. BioRxiv. 2025 June 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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