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SARS-CoV-2-IN-119

CAT: 0804-HY-175829Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175829Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SARS-CoV-2-IN-119 (Compound A28) is a SARS-CoV-2 fusion inhibitor. SARS-CoV-2-IN-119 strongly inhibits Omicron entry with an EC50s of 1.95 and 1.08 μM for pOmicron (BA.2.86.1) and wild Omicron. SARS-CoV-2-IN-119 also has antiviral activities against wild SARS-CoV-2 and other variants, such as pseudotyped Delta SARS-CoV-2, pOmicron (BA.4) and (KP.3) . SARS-CoV-2-IN-119 directly interferes with Omicron S2-mediated viral membrane fusion to block Omicron virus into host cells. SARS-CoV-2-IN-119 can be used for COVID-19 research[1].
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C([C@@H]1N(C(C2=C[C@H](O)[C@H](O)[C@@H](O)C2)=O)C[C@@H](OC(C3=C[C@@H](O)[C@H](O)[C@H](O)C3)=O)C1)O[C@H]4CC[C@]5(C)C6CC=C7C8CC(C)(C)CC[C@]8(C(NCCC9=CC=CC=C9)=O)CC[C@@]7(C)[C@]6(C)CCC5C4(C)C
Molecular Formula
C57H80N2O12
Molecular Weight
985.25
References & Citations
[1]Hong C, et al. Discovery and optimization of OA amide derivatives containing a trisubstituted l-hydroxyproline fragment as novel Omicron fusion inhibitors. Eur J Med Chem. 2025 Dec 5;299:118058.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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