Products for Research Use Only
RegisterLogin

IDOR-1104-0086

CAT: 0804-HY-175668-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175668-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IDOR-1104-0086 is an orally active Kv7 potassium channel opener with an EC50 of 210 nM that can cross blood-brain barrier. IDOR-1104-0086 displays strong selectivity against the hERG channel with an IC20 of 25 μM. IDOR-1104-0086 exhibits efficacy in two rodent models of epilepsy and a favorable tolerability profile. IDOR-1104-0086 can used for the study of epilepsy[1].
CAS Number
2756581-81-2
UNSPSC
12352100
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Purity
98.98
Smiles
O=C(NCC1=CC=CC(C(F)(F)F)=C1)NC2(C3)CC3(C(F)F)C2
Molecular Formula
C15H15F5N2O
Molecular Weight
334.28
References & Citations
[1]Siegrist R, et al. Discovery and In-Vivo Characterization of Kv7 Channel Openers through a Phenotypic Approach. J Med Chem. 2025 Aug 28;68 (16) :17412-17426.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Voltage-gated potassium channel

Related Products

CatalogName
HY-158002-01IDOR-4
HY-162495-01IDOR-1117-2520
HY-162495A-01(S) -IDOR-1117-2520
HY-P991325CRB-0089
HY-144651-01IDO1-IN-18
HY-145355IDO1-IN-12
HY-151093-01IDO2-IN-1
HY-144652-01IDO1-IN-19
HY-178954IDO1-IN-32
HY-178024IDO1-IN-29

Alternative Products

CatalogName
GTR19273059-01IDOR-1104-0086
T86705-01IDOR-1117-2520
GTR19192831-01RS 116 0086
GTR19222007-01Compound 0579-0086
M12894FAUC 1104
286744MINIPIC 1104 AC Signs
P4318PCMV-SPORT6-GATAD2A (1104-1905bp)
PVT13532pCMV-SPORT6-GATAD2A(1104-1905bp) Plasmid
NBP2-79742-20ugMouse Monoclonal Pax2 Antibody (PAX2/1104)
050-51[Cys0]-CMR-1 (1080 - 1104) (Rat)

Popular Products