Products for Research Use Only
RegisterLogin

Yoda2

CAT: 0804-HY-175416-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175416-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Yoda2 (KC289) is the potassium salt of Yoda1. Yoda2 is an agonist of PIEZO1 with an EC50 of 150 nM. Yoda2 evokes Ca2+ elevation in HeLa cells. Yoda2 can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50 = 1.2 μM). Yoda2 can stimulate NOS3 and NO production[1].
CAS Number
3081450-95-2
Product Name Alternative
KC289
UNSPSC
12352005
Target
NO Synthase; Piezo Channel
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.57
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O[K])C1=CC=C(C2=NN=C(SCC3=C(Cl)C=CC=C3Cl)S2)C=C1
Molecular Formula
C16H9Cl2KN2O2S2
Molecular Weight
435.39
References & Citations
[1]Parsonage, G., et al., (2023) . Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. British journal of pharmacology, 180 (16), 2039–2063.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-18723-01Yoda 1

Alternative Products

CatalogName
T211683-01Yoda2

Popular Products