OICR-41103

• Description :

  OICR-41103 is an effective, selective, cell-active DCAF1 small molecule chemical probe that targets the DCAF1 WDR domain and replaces the viral Vpr protein. The binding Ki value of OICR-41103 and DCAF1 is less than 2 nM[1].

• UNSPSC :

  12352005

• Target :

  Ligands for E3 Ligase

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Infection

• Smiles :

  NC(C[C@@H](C1=CC=C(C(Cl)=C1)F)NC(C2=CNC(/C=C/C(N3CCCCC3)=O)=C2C4=C(C=C(C=C4)Cl)F)=O)=O

• Molecular Formula :

  C28H26Cl2F2N4O3

• Molecular Weight :

  575.43

• References & Citations :

  [1]Kimani SW, et al. OICR-41103 as a chemical probe for the DCAF1 WD40 domain. Commun Biol. 2025 Jul 19;8 (1) :1076.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported