OICR-8268

• Target:

  Ligand for E3 Ligase

• Related Pathways:

  PROTAC

• Bioactivity:

  OICR-8268 is a reversible ligand for the DCAF1 WDR domain, exhibiting a Kd of 38 nM, and facilitates the development of DCAF1-based PROTACs [1].

• Smiles:

  C (N[C@@H] (CC (N) =O) C1=CC (Cl) =C (F) C=C1) (=O) C=2C (=NNC2) C3=C (F) C=C (Cl) C=C3

• Molecular Formula:

  C19H14Cl2F2N4O2

• Molecular Weight:

  439.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3000549-26-5