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PDGFRA-IN-1

CAT: 0804-HY-175212Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175212Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDGFRA-IN-1 (Compound 4p) is a Platelet-derived growth factor receptor A (PDGFRA) inhibitor with an IC50 of 1.25 μM. PDGFRA-IN-1 has a significant anticancer activity and potently kills cancer cells including primary patient-derived glioma cells[1].
UNSPSC
12352005
Target
PDGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C1C2=C(NC3=NC4=CC=CC=C4N3C2C5=C(C)N=CN5)CC(C6=CC=CC=C6)C1
Molecular Formula
C24H21N5O
Molecular Weight
395.46
References & Citations
[1]Parmar MP, et al. Ethanol-mediated one-pot synthesis of 3-phenyl-3,4,5,12-tetrahydrobenzo[4,5]imidazo[2,1-b]quinazolin-1 (2H) -ones as PDGFRA inhibitors. Eur J Med Chem. 2025 Jul 4;297:117914.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDGFRα

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