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KIT/PDGFRA-IN-1

CAT: 0013-GTR19249036-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249036-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KIT/PDGFRA-IN-1 (compound 19) is a dual inhibitor of wild-type and mutant KIT and PDGFRA kinases, with IC50 values ranging from sub-micromolar to high micromolar across various isoforms. Its cellular activity, demonstrated by GR50 values in GIST lines, supports its use as a research tool for investigating tyrosine kinase signaling in cancers like gastrointestinal stromal tumors.
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CC (C=CC (C (NC1=CC (C (F) (F) F) =C (NC (C=C) =O) C=C1) =O) =C2) =C2C#CC3=CN=C4N3N=CC=C4
Molecular Formula
C26H18F3N5O2
Molecular Weight
489.449
Storage Conditions
-20°C
Notes
For research use only.

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