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EGFR-IN-166

CAT: 0804-HY-175173Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175173Size:1 Each
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Description
EGFR-IN-166 (Compound 2) is a EGFR inhibitor. EGFR-IN-166 has potent anticancer activity against breast cancer cells with IC50s of 69.63 and 22.84 μM for MCF-7 and MDA-MB-231 cells, respectively. EGFR-IN-166 significantly inhibits cell migration and EGFR expression. EGFR-IN-166 can be used for breast cancer research[1].
CAS Number
503443-98-9
UNSPSC
12352005
Target
EGFR
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C1CN(C2=CC=CC=C2)/C(S1)=C3C(C)=NN(C4=CC=CC=C4)C/3=O
Molecular Formula
C19H15N3O2S
Molecular Weight
349.41
References & Citations
[1]Mahmoud SE, et al. Discovery and molecular characterization of a potent thiazolyl-pyrazole hybrid targeting EGFR for breast cancer therapy. Sci Rep. 2025 Jul 3;15 (1) :23743.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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