Products for Research Use Only
RegisterLogin

HK-2-IN-1

CAT: 0804-HY-175035-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175035-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HK-2-IN-1 is a Hexokinase 2 (HK-2) inhibitor. HK-2-IN-1 exhibits a non-activating effect on human recombinant HK-2 enzyme. HK-2-IN-1 has anti-tumor activity, affecting immune cells in the tumor microenvironment. HK-2-IN-1 has immunomodulatory effects and is potentially useful in the study of cancers such as colon cancer, liver cancer, and breast cancer[1].
UNSPSC
12352005
Target
Hexokinase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Purity
99.88
Smiles
ClC(C=C1Cl)=CC=C1CN(C2=CC(F)=CC=C23)N=C3C4=NC(CC5=CC=CC=C5)=NN4
Molecular Formula
C23H16Cl2FN5
Molecular Weight
452.31
References & Citations
[1]Şavluğ İpek Ӧ, et al. Anti-cancer efficacy of novel lonidamine derivatives: Design, synthesis, in vitro, in vivo, and computational studies targeting hexokinase-2. Eur J Med Chem. 2025 Oct 15;296:117890.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-168717HK-2-IN-2
HY-W131797-011-Iodoethane-1,1,2,2,2-d5
HY-W752879Succinyl (choline-1,1,1',1',2,2,2',2') Bromide-d8
HY-W007978B-011,1'-Binaphthyl-2,2'-diamine
HY-W154117-012,2-Dichloro-1,1-ethanediol
HY-W3941233-Azetidinepropanenitrile, 2,2,2-trifluoroacetate (1:1)
HY-W719128-01Propane-1,1,2-d3-1,2-diol
HY-W703828-011,2-Bis (2,4,6-tribromophenoxy) ethane-1,1,2,2-d4
HY-151344-01HIF-1/2α-IN-2
HY-105253-01PARP-2/1-IN-2

Alternative Products

CatalogName
T211549-01HK-2-IN-1
pka-227HK-2
pka-226HK-1
TRV-055778Human HK-2 Tubular Epithelial Cells (HK-2)
BC1016-1HK-2 Cells
RWT-169HK-2 Cell Line
32-3030-10HK-2 Recombinant Protein
TRV-055791Human NPC/HK-1 Nasopharyngeal Carcinoma Cells (NPC/HK-1)
32-3029-10HK-1 Recombinant Protein
RWT-243HK-1 Cell Line

Popular Products