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CF-Carvacrol

CAT: 0804-HY-175005Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175005Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CF-Carvacrol is an orally active lipid-lowering agent synthesized by merging the pharmacophores of Carvacrol and Clofibric acid (HY-B1415). CF-Carvacrol has a good affinity for PPAR-α. CF-Carvacrol has significant hypolipidemic activity and may exert antioxidant and anti-inflammatory activity by activating the Nrf2/HO-1 signaling pathway to reduce liver injury. CF-Carvacrol can be used for the study of CF-induced liver damage[1].
UNSPSC
12352005
Target
Interleukin Related; Keap1-Nrf2; PPAR
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
CC(C1=CC(OC(C(C)(OC2=CC=C(C=C2)Cl)C)=O)=C(C=C1)C)C
Molecular Formula
C20H23ClO3
Molecular Weight
346.85
References & Citations
[1]Shi X, et al. Optimization of clofibrate by carvacrol results in a new hypolipidemic compound with low hepatic injury. Bioorg Med Chem Lett. 2025 May 1;120:130116./
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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