AMPA-IN-2

• Description :

  AMPA-IN-2 is an orally active AMPA inhibitor that can cross the blood-brain barrier. AMPA-IN-2 improves epileptic seizures by inhibiting the intrinsic excitability of neurons and inhibiting the excitability of glutamatergic transmission. AMPA-IN-2 exerts anti-epileptic effects in the pentylenetetrazol (PTZ) model and can be used as a promising candidates with high broad-spectrum anti-epileptic potential[1].

• UNSPSC :

  12352100

• Target :

  IGluR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  C[C@]12[C@](O)(C[C@@H](CC2)C1(C)C)C#C

• Molecular Formula :

  C12H18O

• Molecular Weight :

  178.27

• References & Citations :

  [1]Zhou X, et al. Discovery of 2-Ethynylisoborneol as a Highly Potent Anti-seizure Agent. J Med Chem. 2025 Jun 23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [75828-06-7]