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AMPA-IN-2

CAT: 0804-HY-174899Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174899Size:1 Each
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Description
AMPA-IN-2 is an orally active AMPA inhibitor that can cross the blood-brain barrier. AMPA-IN-2 improves epileptic seizures by inhibiting the intrinsic excitability of neurons and inhibiting the excitability of glutamatergic transmission. AMPA-IN-2 exerts anti-epileptic effects in the pentylenetetrazol (PTZ) model and can be used as a promising candidates with high broad-spectrum anti-epileptic potential[1].
CAS Number
75828-06-7
UNSPSC
12352100
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C[C@]12[C@](O)(C[C@@H](CC2)C1(C)C)C#C
Molecular Formula
C12H18O
Molecular Weight
178.27
References & Citations
[1]Zhou X, et al. Discovery of 2-Ethynylisoborneol as a Highly Potent Anti-seizure Agent. J Med Chem. 2025 Jun 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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