DSPE-PEG2000-Azide (ammonium)

• Description:

  DSPE-PEG2000-Azide ammonium is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery[1]. DSPE-PEG2000-Azide ammonium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• UNSPSC:

  12352200

• Target:

  Liposome

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Smiles:

  CCCCCCCCCCCCCCCCCC(OCC(COP([O-])(OCCNC(OCCOCCN=[N+]=[N-])=O)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O.[n].[NH4+]

• Molecular Formula:

  (C2H4O) nC44H84N4O10P.NH4

• References & Citations:

  [1]Reyes-Esteves S, et al. Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage. J Control Release. 2023 Apr;356:185-195.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [1938081-40-3]