DSPE-PEG2000-triGalNAc (ammonium)

• UNSPSC Description:

  DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR).

• Target Antigen:

  Liposome

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dspe-peg2000-trigalnac-ammonium.html

• Purity:

  97.4

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCCCCCCCCCCCCC(O[C@]([H])(COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(COCCOCC(NCCCCC(N(CC(NCCOCCOCCO[C@H]1O[C@H]([C@H]([C@H]([C@@H]1NC(C)=O)O)O)CO)=O)CC(NCCOCCOCCO[C@H]2O[C@H]([C@H]([C@H]([C@@H]2NC(C)=O)O)O)CO)=O)C(NCCOCCOCCO[C@H]3O[C@H]([C@H]([C@H]([C@@H]3NC(C)=O)O)O)CO)=O)=O)=O)([O-])=O)=O.[NH4+].[n]

• Molecular Weight:

  2000(Average)

• References & Citations:

  [1]Green Ahn, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021, 17, 9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2936651-86-2