TRPM2-IN-1

• Description :

  TRPM2-IN-1 (compound D10) is a potent TRPM2 inhibitor. TRPM2-IN-1 exhibits antistroke activity and significant neuroprotective effect. TRPM2-IN-1 can be used in the study of ischemic stroke[1].

• UNSPSC :

  12352005

• Target :

  TRP Channel

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(C1=CC(C(N(CC)CC)=O)=CC2=CC=CN21)C3=CC=CC=C3

• Molecular Formula :

  C20H20N2O2

• Molecular Weight :

  320.39

• References & Citations :

  [1]Lu T, et al. Indolizine Derivatives Inhibit TRPM2 and Protect against Ischemic Brain Injury with an Extended Treatment Window. J Med Chem. 2025 Apr 10;68 (7) :7642-7661.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2833727-43-6]