K-5a2

• Description:

  K-5a2 is the non-isotopic form of ZK-316 (HY-173427S) . ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 value ranging from 0.99 to 75.1 nM. ZK-316 can be used in the study of HIV[1].

• UNSPSC:

  12352005

• Target:

  HIV; Reverse Transcriptase

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  N#CC1=CC(C)=C(OC2=C3SC=CC3=NC(NC4CCN(CC4)CC5=CC=C(C=C5)S(=O)(N)=O)=N2)C(C)=C1

• Molecular Formula:

  C27H28N6O3S2

• Molecular Weight:

  548.68

• References & Citations:

  [1]Zhang K, et al. Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability. J Med Chem. 2025 Apr 24;68 (8) :8564-8577.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1810730-10-9]