STAT4-IN-1

• Description:

  STAT4-IN-1 is an inhibitor of STAT4 with a Ki of 0.35 μM. STAT4-IN-1 is expected to be used in the research of autoimmune diseases, including inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, and diabetes[1].

• UNSPSC:

  12352005

• Target:

  STAT

• Related Pathways:

  JAK/STAT Signaling; Stem Cell/Wnt

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Purity:

  99.17

• Solubility:

  DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  FC1=C(OP(O)(O)=O)C=CC(C2=CC=C3C(C=CC=C3)=C2)=C1

• Molecular Formula:

  C16H12FO4P

• Molecular Weight:

  318.24

• References & Citations:

  [1]Brovchenko N, et al. Biaryl Phosphates and Phosphonates as Selective Inhibitors of the Transcription Factor STAT4. Angew Chem Int Ed Engl. 2025 Mar 11:e202504420.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported