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TrkC-IN-1

CAT: 0804-HY-173227Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173227Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TrkC-IN-1 (Compound 6c) is an inhibitor of TrkC. The IC50 values for EBC-1 and HT-29 cells are 3.3-7.1 and 7.3-10.2 μΜ, respectively. TrkC-IN-1 is expected to be used in the research of the anti-cancer field[1].
CAS Number
1877313-32-0
UNSPSC
12352005
Target
Trk Receptor
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
BrC1=CC=C(CN2C3=CC=CC=C3C4(C2=O)C5=C(OC(N)=C4C#N)N(C6=CC=CC=C6)N=C5C)C=C1
Molecular Formula
C28H20BrN5O2
Molecular Weight
538.39
References & Citations
[1]Mohammadi S, et al. Novel spiroisatin-pyranopyrazole hybrids as anticancer agents with TrkC inhibitory potential. J Biomol Struct Dyn. 2025 Mar 2:1-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TrkC

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