TrkC-IN-1

• Description:

  TrkC-IN-1 (Compound 6c) is an inhibitor of TrkC. The IC50 values for EBC-1 and HT-29 cells are 3.3-7.1 and 7.3-10.2 μΜ, respectively. TrkC-IN-1 is expected to be used in the research of the anti-cancer field[1].

• UNSPSC:

  12352005

• Target:

  Trk Receptor

• Related Pathways:

  Neuronal Signaling; Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Smiles:

  BrC1=CC=C(CN2C3=CC=CC=C3C4(C2=O)C5=C(OC(N)=C4C#N)N(C6=CC=CC=C6)N=C5C)C=C1

• Molecular Formula:

  C28H20BrN5O2

• Molecular Weight:

  538.39

• References & Citations:

  [1]Mohammadi S, et al. Novel spiroisatin-pyranopyrazole hybrids as anticancer agents with TrkC inhibitory potential. J Biomol Struct Dyn. 2025 Mar 2:1-14.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  TrkC

• CAS Number:

  [1877313-32-0]