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TrkB-IN-1

CAT: 0804-HY-153189-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153189-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TrkB-IN-1 is a potent and orally active TrkB agonist and has favorable PK properties. TrkB-IN-1 reverses the cognitive defects in an AD mouse model and can be used for alzheimer’s disease research[1].
CAS Number
1609067-49-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trkb-in-1.html
Purity
99.2
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC=C2)OC3=C(OC(NC)=O)C(OC(NC)=O)=CC=C13
Molecular Formula
C19H16N2O6
Molecular Weight
368.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Chun Chen, et al. The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 Jan 16;115 (3) :578-583.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TrkB

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