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PSF-IN-2

CAT: 0804-HY-173177-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-173177-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PSF-IN-2 (Compound (C) -30) is a PSF inhibitor with an IC50 value of 0.005 pM. PSF-IN-2 exhibits anti-cancer activity, and its IC50 value for inhibiting the proliferation of 22Rv1 cells is 0.5 μM. PSF-IN-2 activates the p53 signaling pathway by inhibiting the binding of PSF to RNA, inducing the expression of related genes, promoting apoptosis, and inhibiting the cell cycle. PSF-IN-2 can be used in cancer research[1].
CAS Number
185418-37-5
UNSPSC
12352005
Target
Apoptosis; MDM-2/p53
Related Pathways
Apoptosis
Field of Research
Cancer
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1OC2=C(C(C3=CC=C(OC)C=C3)=C1)C=CC(OC)=C2OC
Molecular Formula
C18H16O5
Molecular Weight
312.32
References & Citations
[1]Takayama KI, et al. Inhibition of PSF Activity Overcomes Resistance to Treatment in Cancers Harboring Mutant p53. Mol Cancer Ther. 2025 Mar 4;24 (3) :370-383.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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