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PSF-IN-2

CAT: 0931-T206152-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206152-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
185418-37-5
Target
MDM-2/p53, Apoptosis
Related Pathways
Apoptosis
Bioactivity
PSF-IN-2 (Compound (C) -30) is a PSF inhibitor with an IC50 value of 0.005 pM. It exhibits anticancer properties, inhibiting the proliferation of 22Rv1 cells with an IC50 value of 0.5 μM. PSF-IN-2 activates the p53 signaling pathway by disrupting PSF-RNA binding, inducing expression of related genes, promoting apoptosis, and inhibiting the cell cycle. This compound is applicable in cancer research.
Smiles
O=C1OC=2C(OC)=C(OC)C=CC2C(=C1)C=3C=CC(OC)=CC3
Molecular Formula
C18H16O5
Molecular Weight
312.317
Shipping Conditions
Ice Packs
Storage Temperature
-20°C