RegisterLogin

CDK2-IN-45

CAT: 0804-HY-172872Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-172872Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CDK2-IN-45 (Compound 8f) is a CDK2 inhibitor (IC50: 0.64 μM) . CDK2-IN-45 inhibits the proliferation of DU-145 and PC-3 cell lines with IC50 of 2.20 μM and 4.17 μM, respectively. CDK2-IN-45 induces G0/G1 cell cycle arrest and apoptosis. CDK2-IN-45 can be used in prostate cancer research[1].
UNSPSC
12352101
Target
Apoptosis; CDK
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
ClC(C=C1)=CC=C1C2=CC=NC3=C(C(NC4=CC=CC=C4)=NN32)C5=NC6=C(S5)C=CC=C6
Molecular Formula
C25H16ClN5S
Molecular Weight
453.95
References & Citations
[1]Elkotamy MS, et al. Development of Benzothiazole-grafted Pyrazolo[1,5-a]pyrimidines as new CDK2 inhibitors and anti-prostate cancer agents. Bioorg Chem. 2025 May 7;161:108565.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2

Related Products

CatalogName
HY-179023CDK9-IN-45
HY-P0235CDK2
HY-134622-01GSK-3/CDK5/CDK2-IN-1
HY-160941CDK2-IN-29
HY-150572CDK2-IN-11
HY-176174SCDK2-IN-46
HY-177957CDK2-IN-52
HY-179161CDK2-IN-49
HY-155441CDK2-IN-20
HY-160643CDK2-IN-27

Alternative Products

CatalogName
T207142-01CDK2-IN-45
S0273-5mgCDK2-IN-73 (CDK2-IN-4)
MBS8534723-01CDK2
MBS8513868-01CDK2 Antibody
TS417634P5CDK2 CytoSection
505651-01CDK2 discontinued
117168Human CDK2

Popular Products