DEL-I25

• Description:

  DEL-I25 is a potent GPX4 activator. DEL-I25 protects cells from ferroptosis[1].

• UNSPSC:

  12352005

• Target:

  Glutathione Peroxidase

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(N1CC(NC(CCC2=CC=C(N)C=N2)=O)C1)CN3C(C4=CC=CC=C4C3)=O

• Molecular Formula:

  C21H23N5O3

• Molecular Weight:

  393.44

• References & Citations:

  [1]Liu H, et al. Selective Small-Molecule Activator of Patient-Derived GPX4 Variant. ACS Chem Biol. 2025 May 16;20 (5) :1107-1122.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  GPX4

• CAS Number:

  [3036889-54-7]