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(±) 5 (6) -EET Ethanolamide

CAT: 0804-HY-172568Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172568Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) 5 (6) -EET Ethanolamide is a metabolite of Anandamide generated via oxidation by cytochrome P450 enzymes. (±) 5 (6) -EET Ethanolamide is also a selective cannabinoid receptor 2 (CB2) agonist. (±) 5 (6) -EET Ethanolamide has Ki values of 11.4 μM and 8.9 nM for human CB1 and CB2, respectively. (±) 5 (6) -EET Ethanolamide can be used in research on immunomodulation and neuroinflammation[1].
UNSPSC
12352211
Target
Cannabinoid Receptor; Cytochrome P450
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
CCCCC/C=C\C/C=C\C/C=C\C[C@H]1O[C@H]1CCCC(NCCO)=O
Molecular Formula
C22H37NO3
Molecular Weight
363.53
References & Citations
[1]Snider NT, et al. A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. Mol Pharmacol. 2009 Apr;75 (4) :965-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1; CB2

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