(±) 5 (6) -EET Ethanolamide

• Description:

  (±) 5 (6) -EET Ethanolamide is a metabolite of Anandamide (HY-10863) generated via oxidation by cytochrome P450 enzymes. (±) 5 (6) -EET Ethanolamide is also a selective cannabinoid receptor 2 (CB2) agonist. (±) 5 (6) -EET Ethanolamide has Ki values of 11.4 μM and 8.9 nM for human CB1 and CB2, respectively . (±) 5 (6) -EET Ethanolamide can be used in research on immunomodulation and neuroinflammation[1].

• UNSPSC:

  12352211

• Target:

  Cannabinoid Receptor; Cytochrome P450

• Related Pathways:

  GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  CCCCC/C=C\C/C=C\C/C=C\C[C@H]1O[C@H]1CCCC(NCCO)=O

• Molecular Formula:

  C22H37NO3

• Molecular Weight:

  363.53

• References & Citations:

  [1]Snider NT, et al. A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. Mol Pharmacol. 2009 Apr;75 (4) :965-72.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB1; CB2