Products for Research Use Only
RegisterLogin

BI-5756

CAT: 0804-HY-171883Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-171883Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BI-5756 is a CETP inhibitor and cannabinoid receptor 1 (CB1) agonist. BI-5756 can significantly increase HDL-C levels and reduce LDL-C levels. BI-5756 can also enhance the function of regulatory T cells while maintaining T cell-mediated anti-tumor activity. BI-5756 can directly inhibit the growth of tumor cells and upregulate the expression of MHC I, MHC II, and CD80 on tumor cells. BI-5756 has a protective effect in graft-versus-host disease models. BI-5756 can be used in research on tumors, graft-versus-host disease, and metabolic diseases[1].
CAS Number
1332485-18-3
UNSPSC
12352005
Target
Cannabinoid Receptor; CETP; MHC
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Smiles
CC(C1=NC(CC(C)(C[C@@H]2O)C)=C2C3=C1[C@@H](C4=CC=C(C=C4)C(F)(F)F)OC35CCOCC5)C
Molecular Formula
C27H32F3NO3
Molecular Weight
475.54
References & Citations
[1]Kim S, et al. BI-5756 Reduces Graft-Versus-Host Disease Through CB1-Mediated Treg Upregulation. Molecules. 2025 Aug 28;30 (17) :3517.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-112282BI-1408
HY-P991488-01BI-765423
HY-P991192-01BI-1808
HY-123800-01BI 187004
HY-111925-01BI-749327
HY-124772-01BI-2545
HY-126253-01BI-4916
HY-124063-01BI-1935
HY-108705-01BI-3802
HY-103661-01BI-6C9

Alternative Products

CatalogName
GTR19273214-01BI-5756
B2798-500BI
S0099Scavenger Receptor BI (SR-BI)
MBS131573BI-9564 (BI 9564; BI9564)
SR303880PTK9 (TWF1) Human siRNA Oligo Duplex (Locus ID 5756)
TL320501VPTK9 (TWF1) Human shRNA Lentiviral Particle (Locus ID 5756)
TF320501PTK9 (TWF1) Human shRNA Plasmid Kit (Locus ID 5756)
B6014-50BI-847325
BA3815-5BI-1622
BA6338-5.1BI-4142

Popular Products