PRMT3-IN-5

• Description:

  PRMT3-IN-5 (Compound 14) is an allosteric PRMT3 inhibitor (IC50: 291 nM) . PRMT3-IN-5 can be used for investigating PRMT3's biological functions and disease associations[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Related Pathways:

  Epigenetics

• Smiles:

  O=C(NCCC1(CCCCC1)CN)NC2=CC3=C(C=NC=C3)C=C2

• Molecular Formula:

  C19H26N4O

• Molecular Weight:

  326.44

• References & Citations:

  [1]Kaniskan HÜ, et al. Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3) . J Med Chem. 2018 Feb 8;61 (3) :1204-1217.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PRMT3

• CAS Number:

  2204250-25-7