Products for Research Use Only

GABAA receptor modulator-4

CAT: 0804-HY-170902Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-170902Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GABAA receptor modulator-4 (Compound 4) is the negative allosteric modulator for GABAA receptor. GABAA receptor modulator-4 inhibits α1β3γ2 GABAA receptor-mediated peak and steady currents with IC50 of 10 μM and 10 μM[1].
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
BrC(C=C1)=CC2=C1[C@]3(C)C(C[C@@H](OS(=O)(O)=O)CC3)=CC2
Molecular Formula
C15H17BrO4S
Molecular Weight
373.26
References & Citations
[1]Xu Y, et al., Design, Synthesis, and Pharmacological Evaluation of Nonsteroidal Tricyclic Ligands as Modulators of GABAA Receptors. J Med Chem. 2025 Feb 13;68 (3) :3795-3813.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported