ICD inducer-1

• Description :

  ICD inducer-1 (Compound Re1) is an effective immunogenic cell death (ICD) inducer that can target the endoplasmic reticulum (ER) and block ER-phagy at the late stages. ICD inducer-1 is promising for research of cancers[1].

• UNSPSC :

  12352005

• Target :

  ER-phagy

• Related Pathways :

  Autophagy

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  CC1=CC(C)=[N]2C1=C(C3=CC=[N]([Re+]4(C=O)(C=O)(C=O)[N]5=CC=C6C(NC7=C6C=CC=C7)=C5C8=CC=CC=[N]48)C=C3)C9=C(C)C=C(C)[N-]9[B+3]2([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-]

• Molecular Formula :

  C37H32BF8N6O3PRe

• Molecular Weight :

  988.67

• References & Citations :

  [1]Hao L, et al. Theranostic Rhenium (I) -Based ER-Phagy Retardant Promotes Immunogenic Cell Death. J Med Chem. 2025 Jan 9;68 (1) :338-347.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported