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Hypoxia inducer-1

CAT: 0804-HY-170774Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170774Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hypoxia inducer-1 (Compound N6) is an orally active hypoxia activated nitric oxide (NO) donor compound. Hypoxia inducer-1 exhibits highly selective NO release under hypoxic conditions and inhibits hypoxia-induced apoptosis, necrosis, and the increase in ROS levels. Hypoxia inducer-1 regulates vascular dilation and has a protective effect in a mouse model of myocardial hypoxia injury. Hypoxia inducer-1 can be used in the research of coronary heart disease[1].
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cardiovascular Disease
Smiles
CN(C1=CC=C(OCC2=CC(F)=C(C=C2)[N+]([O-])=O)C=C1)N=O
Molecular Formula
C14H12FN3O4
Molecular Weight
305.26
References & Citations
[1]Yang W, et al. Hypoxia Activated Nitric Oxide Donor Compounds for the Prevention and Treatment of Myocardial Hypoxia-Induced Injury. J Med Chem. 2025 Jan 9;68 (1) :491-505.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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