(R) -FL118

• Description :

  (R) -FL118 (10,11- (Methylenedioxy) -20 (R) -camptothecin) is the R-enantiomer of FL118 (HY-12486) . (R) -FL118 shows anticancer activity[1].

• Product Name Alternative :

  10,11- (Methylenedioxy) -20 (R) -camptothecin

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Drug Derivative

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/r-fl118.html

• Purity :

  99.94

• Solubility :

  DMSO : 2.7 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC6=C(OCO6)C=C5C=C4C3)=C2)=O)O

• Molecular Formula :

  C21H16N2O6

• Molecular Weight :

  392.36

• Precautions :

  H301

• References & Citations :

  [1]Del Poeta M, et al. Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. Antimicrob Agents Chemother. 1999 Dec;43 (12) :2862-8.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [151636-76-9]