CG-3-246

CAT: 0804-HY-170689Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170689Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CG-3-246 is a dual inhibitor of FLT3/BCL-2, with the Kds of 63 and 4.25 nM, respectibely. CG-3-246 plays an important role in acute myeloid leukemias research[1].
UNSPSC
12352005
Target
Bcl-2 Family; FLT3
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC=C(N4CCN(C(CNC5=CC=C(S(=O)(NC(C6=CC=C(N7CCN(CC8=C(C9=CC=C(Cl)C=C9)CC(C)(C)CC8)CC7)C=C6OC%10=CN=C(NC=C%11)C%11=C%10)=O)=O)C=C5[N+]([O-])=O)=O)CC4)C(OC)=C3)N
Molecular Formula
C64H73ClN14O10S
Molecular Weight
1265.87
References & Citations
[1]Christopher C Goodis, et al. The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN–GIL hybrid single-molecule inhibitors. Eur J Med Chem. 2024 Dec 22:285:117190.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-115568-01BETd-246
HY-112646CG-806
HY-114877CG-707
HY-W999638CRBN ligand-246
HY-168109Antibacterial agent 246
HY-P7893-01CG beta 3, Human (HEK293, His)
HY-138516CG-PEG5-azido
HY-P75342-01CG alpha, Human (HEK293)
HY-D1287Serum CG probe 2
HY-D1286Serum CG probe 1

Alternative Products

CatalogName
MF-0112838-01CG-3-246
M13420-01BETd-246
M14875-01APR-246
S-3555246-Tribromophenol
MBS133351ML-246
S-3645246-Trichlorophenol
7425/5CG 428
GWB-4BC292CG Antibody
MBS3844266-01CG-806
MBS3845375-01CG-200745

Popular Products