CG-3-246

• Target :

  Bcl-2 Family|||FLT

• Related Pathways :

  Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  CG-3-246 is a dual inhibitor targeting FLT3 and BCL-2, with dissociation constants (Kd) of 63 nM and 4.25 nM, respectively. This compound plays a significant role in acute myeloid leukemia research.

• Smiles :

  CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCN(CC3)C(=O)CNC4=C(C=C(C=C4)S(=O)(=O)NC(=O)C5=C(C=C(C=C5)N6CCN(CC6)CC7=C(CC(CC7)(C)C)C8=CC=C(C=C8)Cl)OC9=CN=C1C(=C9)C=CN1)[N+](=O)[O-])OC)NC1CCOCC1

• Molecular Formula :

  C64H73ClN14O10S

• Molecular Weight :

  1265.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C