Products for Research Use Only
RegisterLogin

SMase-IN-1

CAT: 0804-HY-170650Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-170650Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase enzyme (SMase) inhibitor (IC50 value for B. cereus SMase is 6.43 µM) . SMase-IN-1 also inhibits eqBuChE (59.50% inhibition rate at 50 µM concentration) . SMase-IN-1 forms a complex with Cu2+ in biometal interactions. SMase-IN-1 reduces B. cereus-induced hemolysis on sheep erythrocytes[1].
CAS Number
33017-85-5
UNSPSC
12352005
Target
Bacterial; Cholinesterase (ChE) ; Phospholipase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Smiles
O=C(C1=CC(Cl)=CC=C1N2)NC2=S
Molecular Formula
C8H5ClN2OS
Molecular Weight
212.66
References & Citations
[1]Ozturk OK, et al. Quinazoline derivatives as novel bacterial sphingomyelinase enzyme inhibitors. Bioorg Chem. 2025 Jan;154:108079.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-149536TWIK-1/TREK-1-IN-1
HY-W160628S1,1,1-Trimethoxypropane-d5
HY-133630-011-Bromo-1,1-dichloroacetone
HY-W881439-011- (1,1-Dimethylethyl) tridecanedioate
HY-W032015S11-Bromooctane-1,1-d2
HY-1336291,1,1,3-Tetrachloroacetone
HY-112773-011,1′,1′′,1′′′-[1,4-Piperazinediylbis (2,1-ethanediylnitrilo) ]tetrakis[2-dodecanol]

Alternative Products

CatalogName
T204131-01SMase-IN-1
sc-377135N-SMase (B-1)
sc-377135 ACN-SMase (B-1) AC
sc-377135 PEN-SMase (B-1) PE
sc-377135 PN-SMase (B-1) P
sc-377135 HRPN-SMase (B-1) HRP
sc-377135 FITCN-SMase (B-1) FITC
sc-60151Alk-SMase siRNA (h)
sc-106277-PRN-SMase (h) -PR
sc-202721N-SMase Spiroepoxide Inhibitor

Popular Products